Francesco Errico Selected Research

D-Aspartic Acid (D Aspartate)

1/2022	Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain.
12/2020	Dysfunctional d-aspartate metabolism in BTBR mouse model of idiopathic autism.
1/2018	The Emerging Role of Altered d-Aspartate Metabolism in Schizophrenia: New Insights From Preclinical Models and Human Studies.
1/2018	DNA methylation landscape of the genes regulating D-serine and D-aspartate metabolism in post-mortem brain from controls and subjects with schizophrenia.
10/2017	Olanzapine, but not clozapine, increases glutamate release in the prefrontal cortex of freely moving mice by inhibiting D-aspartate oxidase activity.
1/2017	Decreased free d-aspartate levels are linked to enhanced d-aspartate oxidase activity in the dorsolateral prefrontal cortex of schizophrenia patients.
12/2015	D-Aspartate: An endogenous NMDA receptor agonist enriched in the developing brain with potential involvement in schizophrenia.
10/2015	D-aspartate dysregulation in Ddo(-/-) mice modulates phencyclidine-induced gene expression changes of postsynaptic density molecules in cortex and striatum.
1/2015	D-aspartate modulates nociceptive-specific neuron activity and pain threshold in inflammatory and neuropathic pain condition in mice.
10/2013	Decreased levels of D-aspartate and NMDA in the prefrontal cortex and striatum of patients with schizophrenia.

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Francesco Errico Research Topics

Disease

15	Schizophrenia (Dementia Praecox) 01/2022 - 10/2008
6	Mental Disorders (Mental Disorder) 01/2022 - 01/2009
5	Parkinson Disease (Parkinson's Disease) 01/2022 - 12/2011
5	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2013
3	Dyskinesias (Dyskinesia) 01/2019 - 12/2011
2	Cognitive Dysfunction 03/2021 - 01/2013
2	Catalepsy 07/2015 - 06/2010
1	Multiple Sclerosis 12/2021
1	Dementia (Dementias) 03/2021
1	Canavan Disease (Leukodystrophy, Spongiform) 01/2021
1	Autistic Disorder (Autism) 12/2020
1	Neurobehavioral Manifestations 01/2018
1	Pathologic Processes 01/2017
1	Bipolar Disorder (Manic Depressive Psychosis) 01/2017
1	Acute Pain 01/2015
1	Neuralgia (Stump Neuralgia) 01/2015
1	Hyperkinesis 08/2010
1	Dystonia musculorum deformans type 1 06/2010
1	Dystonia (Limb Dystonia) 06/2010
1	Substance-Related Disorders (Drug Abuse) 01/2010

Drug/Important Bio-Agent (IBA)

12	D-Aspartic Acid (D Aspartate)IBA 01/2022 - 10/2008
9	Serine (L-Serine)FDA Link 01/2022 - 10/2008
8	Amino Acids FDA Link 01/2022 - 10/2008
8	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2019 - 01/2009
6	Messenger RNA (mRNA)IBA 01/2022 - 02/2016
4	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2022 - 10/2013
4	Glutamic Acid (Glutamate)FDA Link 01/2022 - 01/2021
4	Haloperidol (Haldol)FDA LinkGeneric 10/2017 - 06/2010
3	Levodopa (L Dopa)FDA LinkGeneric 01/2019 - 12/2011
3	N-Methylaspartate (NMDA)IBA 12/2015 - 12/2011
2	Proteins (Proteins, Gene)FDA Link 01/2022 - 06/2010
2	Dopamine (Intropin)FDA LinkGeneric 01/2022 - 08/2010
2	Aspartic Acid (Aspartate)FDA Link 01/2022 - 01/2017
2	Pharmaceutical PreparationsIBA 03/2021 - 12/2011
2	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2019 - 01/2017
2	Bupropion (Wellbutrin)FDA LinkGeneric 10/2017 - 08/2010
2	D-Aspartate OxidaseIBA 01/2017 - 12/2011
2	EnzymesIBA 01/2017 - 12/2011
2	Amphetamine (Amfetamine)FDA LinkGeneric 08/2010 - 10/2008
1	Glutamine (L-Glutamine)FDA Link 03/2021
1	Valine (L-Valine)FDA Link 01/2021
1	Alanine (L-Alanine)FDA Link 01/2021
1	Threonine (L-Threonine)FDA Link 01/2021
1	Phencyclidine (Angel Dust)IBA 01/2018
1	Fluoxetine (Prozac)FDA LinkGeneric 10/2017
1	Olanzapine (Zyprexa)FDA Link 10/2017
1	Amitriptyline (Elavil)FDA LinkGeneric 10/2017
1	Chlorpromazine (Thorazine)FDA Link 10/2017
1	Clozapine (Clozaril)FDA LinkGeneric 10/2017
1	Antipsychotic Agents (Antipsychotics)IBA 10/2017
1	serine racemaseIBA 01/2017
1	A-factor (Streptomyces)IBA 01/2017
1	Biological ProductsIBA 02/2016
1	GTP-Binding Proteins (G-Protein)IBA 02/2016
1	Cycloserine (Seromycin)FDA Link 10/2015
1	Caffeine (No Doz)FDA LinkGeneric 07/2015
1	PlasticsIBA 01/2015
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2014
1	gantenerumabIBA 01/2013
1	Monomeric GTP-Binding ProteinsIBA 12/2011
1	TOR Serine-Threonine KinasesIBA 12/2011
1	Amantadine (Aman)FDA LinkGeneric 12/2011
1	Nomifensine (Nomifensin)IBA 08/2010
1	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 08/2010
1	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 06/2010
1	Dopamine D2 Receptors (Dopamine D2 Receptor)IBA 06/2010
1	Sucrose (Saccharose)IBA 01/2010
1	Dizocilpine Maleate (Dizocilpine)IBA 10/2008

Therapy/Procedure

3	Therapeutics 01/2018 - 12/2011
1	Activities of Daily Living (ADL) 01/2013